Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data
… We have created a new semantic systems chemical biology resource, and have demonstrated
its potential usefulness in specific examples of polypharmacology, multiple pathway …
its potential usefulness in specific examples of polypharmacology, multiple pathway …
Bright ideas for chemical biology
… biological systems. The importance of fluorescence-based technologies in chemical biology
… Here, we examine the chemical and photophysical properties of oft-used fluorophores and …
… Here, we examine the chemical and photophysical properties of oft-used fluorophores and …
The chemical biology of S-nitrosothiols
KA Broniowska, N Hogg - Antioxidants & redox signaling, 2012 - liebertpub.com
… the biological chemistry of S-nitrosation and to point out where the challenges lie in matching
the known chemical biology of … system in some detail. The importance of these reactions to …
the known chemical biology of … system in some detail. The importance of these reactions to …
Chemistry in living systems
JA Prescher, CR Bertozzi - Nature chemical biology, 2005 - nature.com
… First, we provide an overview of existing chemical reporters and bioorthogonal reactions. …
in cellular systems. Third, we highlight the translation of one chemical reporter system from cell-…
in cellular systems. Third, we highlight the translation of one chemical reporter system from cell-…
Cleavable linkers in chemical biology
G Leriche, L Chisholm, A Wagner - Bioorganic & medicinal chemistry, 2012 - Elsevier
… The recent rise of chemical biology has lead to the demand for cleavable linkers that are
compatible with the biological molecules and systems. Chemists started to reassess potential …
compatible with the biological molecules and systems. Chemists started to reassess potential …
Target identification and mechanism of action in chemical biology and drug discovery
M Schenone, V Dančík, BK Wagner… - … chemical biology, 2013 - nature.com
… extend systems biology to drug-target and ligand-target networks and are now known as 'systems
chemical biology' 134 , 'network pharmacology' 135 or 'systems pharmacology' 136 . …
chemical biology' 134 , 'network pharmacology' 135 or 'systems pharmacology' 136 . …
The nature of systems biology
FJ Bruggeman, HV Westerhoff - TRENDS in Microbiology, 2007 - cell.com
… However, unless the systems biology is carried out … systems biology and discuss two
approaches that are helping to address such challenges: top-down and bottom-up systems biology. …
approaches that are helping to address such challenges: top-down and bottom-up systems biology. …
Applications of microfluidics in chemical biology
DB Weibel, GM Whitesides - Current opinion in chemical biology, 2006 - Elsevier
… in chemical biology. It aims to introduce the reader to microfluidics, describe characteristics
of microfluidic systems that are useful in studying chemical biology, and … in chemical biology. …
of microfluidic systems that are useful in studying chemical biology, and … in chemical biology. …
[图书][B] Systems biology
B Palsson - 2015 - books.google.com
… , molecular biology became focused on the systems properties of cellular and tissue functions.
These are the properties that arise from the whole, and represent biological properties. In …
These are the properties that arise from the whole, and represent biological properties. In …
[HTML][HTML] Applications of cucurbiturils in medicinal chemistry and chemical biology
… areas of medicinal chemistry and chemical biology. Though in … CB-based drug delivery
systems has become overwhelming in the … The stability of the system in biological media was also …
systems has become overwhelming in the … The stability of the system in biological media was also …